ncRNA name | hsa-let-7g* |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell line Y79 |
Methods | MTT assay, fluorescent microscope, flow cytometry, collagenase assay, microarray |
Expression pattern | down-regulated |
Functional description | Results of the microRNA analysis revealed changes in the expression of 52 miRNAs (overexpression of 6 miRNAs; downregulation of 46 miRNAs) in cells grown with PLGA–gelatin microparticles compared to those grown without microparticles. Let-7 miRNAs (let-7 family) and miR-34a may enhance retinoblastoma tumor proliferation. |
PubMed ID | 22690114 |
Year | 2012 |
Title | A novel in vitro three-dimensional retinoblastoma model for evaluating chemotherapeutic drugs. |
Drug-related ncRNA | NO |
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